Saturday, 19 May 2012
Trifexis | Print |

Trifexis-1

5 sizes for dogs: 5-10 lb (pink); 10-20 lb (orange); 20-40 lb (teal); 40-60 lb (blue); 60-120 lb(brown)

Form: chewable flavored tablets

Frequency of administration: monthly

Active ingredients: spinosad (a compound  naturally produced by soil bacteria) and milbemycin oxime

Mode of action:

  • Spinosad : binds to neurological receptors that are unique to insects and quickly causes paralysis that results in death of the flea
  • Milbemycin oxime : inhibits the neurotransmitter GABA in invertebrates leading to paralysis and death of parasites

Adverse effects: vomiting in a small percentage of dogs that usually resolves with subsequent dosages
Notify your veterinarian if vomiting occurs

If vomiting occurs within one hour of administering the dosage, you will need to re-dose on the following day

Contraindications: puppies less than 8 weeks of age and/or less than 5 pounds, dogs with heartworms, breeding females and dogs with epilpesy

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Please contact our veterinarians at Animal Medical